NEET Biology Class 12 Chapter 2 New NCERT: Human Reproduction MCQ 50 Questions with Answers PDF 2027

🧬 Chapter 2: Human Reproduction - HARD LEVEL NEET 2027

Q1. Assertion: Spermatogenesis is temperature dependent. Reason: Scrotum provides 2-3°C lower temperature than body.

a) Both true, Reason correct explanationb) Both true, Reason not correct explanationc) Assertion true, Reason falsed) Both false

Q2. Match List-I with List-II: A. Leydig cells - 1. Nourishment of sperm, B. Sertoli cells - 2. Testosterone, C. Acrosome - 3. Hyaluronidase, D. Middle piece - 4. Mitochondria

a) A-2, B-1, C-3, D-4b) A-1, B-2, C-4, D-3c) A-2, B-3, C-1, D-4d) A-4, B-1, C-2, D-3

Q3. Which of the following statements is INCORRECT regarding menstrual cycle?

a) LH surge induces rupture of Graafian follicleb) Progesterone is secreted by corpus luteum in luteal phasec) FSH levels are highest during ovulationd) Endometrium is shed during menstrual phase

Q4. If a secondary oocyte is fertilized, the resulting zygote will have

a) 23 chromosomesb) 46 chromosomesc) 69 chromosomesd) 92 chromosomes

Q5. Which hormone is responsible for maintaining corpus luteum in early pregnancy?

a) LHb) hCGc) Estrogend) Progesterone

Q6. The failure of testes to descend into scrotum leads to

a) Azoospermiab) Cryptorchidism and sterilityc) Gynecomastiad) Impotency

Q7. Which layer of blastocyst attaches to endometrium during implantation?

a) Inner cell massb) Trophoblastc) Zona pellucidad) Blastocoel

Q8. Assertion: Placenta acts as an endocrine gland. Reason: It secretes hCG, estrogen and progesterone.

a) Both true, Reason correct explanationb) Both true, Reason not correct explanationc) Assertion true, Reason falsed) Both false

Q9. The fluid in seminiferous tubules is called

a) Seminal plasmab) Tubular fluidc) Interstitial fluidd) Lymph

Q10. Which of the following is NOT a function of Sertoli cells?

a) Phagocytosis of residual bodiesb) Secretion of ABPc) Secretion of testosteroned) Nourishment of spermatids

Q11. The capacitation of sperm occurs due to

a) Removal of glycoprotein coat and seminal plasma proteinsb) Addition of fructosec) Entry into uterusd) Action of testosterone

Q12. In humans, the zygote undergoes cleavage to form 16-celled stage called

a) Morulab) Blastulac) Gastrulad) Blastocyst

Q13. Which of the following is correct sequence of sperm transport?

a) Seminiferous tubules → Rete testis → Vasa efferentia → Epididymis → Vas deferensb) Seminiferous tubules → Epididymis → Rete testis → Vas deferensc) Rete testis → Seminiferous tubules → Epididymis → Vas deferensd) Vas deferens → Epididymis → Rete testis

Q14. The hormone relaxin is secreted by

a) Placenta and ovaryb) Pituitaryc) Hypothalamusd) Adrenal

Q15. Assertion: Oogenesis is discontinuous. Reason: Primary oocytes are formed before birth but complete meiosis I only after puberty.

a) Both true, Reason correct explanationb) Both true, Reason not correct explanationc) Assertion true, Reason falsed) Both false

Q16. The endometrium shows maximum thickness during

a) Menstrual phaseb) Proliferative phasec) Secretory phased) Ovulation

Q17. Which structure prevents polyspermy?

a) Zona reactionb) Acrosome reactionc) Capacitationd) Cortical reaction

Q18. Match: A. Menarche - 1. Cessation of cycle, B. Menopause - 2. First menstruation, C. Ovulation - 3. Release of ovum, D. Gestation - 4. Pregnancy

a) A-2, B-1, C-3, D-4b) A-1, B-2, C-4, D-3c) A-3, B-4, C-1, D-2d) A-4, B-3, C-2, D-1

Q19. The embryonic membrane that forms placenta is

a) Amnionb) Chorionc) Allantoisd) Yolk sac

Q20. Which of the following is not secreted by placenta?

a) hCGb) hPLc) Relaxind) LH

Q21. The failure of implantation leads to

a) Ectopic pregnancyb) Abortionc) Menorrhagiad) Dysmenorrhea

Q22. Assertion: Colostrum is rich in IgA. Reason: It provides passive immunity to newborn.

a) Both true, Reason correct explanationb) Both true, Reason not correct explanationc) Assertion true, Reason falsed) Both false

Q23. The number of polar bodies formed from 1 primary oocyte is

a) 1b) 2c) 3d) 4

Q24. Which cells are diploid in testis?

a) Spermatogonia and Sertoli cellsb) Primary spermatocyte and spermatidc) Sperm and spermatidd) Secondary spermatocyte and sperm

Q25. The part of fallopian tube where fertilization occurs

a) Infundibulumb) Ampullac) Isthmusd) Uterine part

Q26. Assertion: Breast feeding delays conception. Reason: Prolactin inhibits GnRH secretion.

a) Both true, Reason correct explanationb) Both true, Reason not correct explanationc) Assertion true, Reason falsed) Both false

Q27. The function of bulbourethral gland is

a) Secrete fructoseb) Lubrication and neutralize acidityc) Secrete testosteroned) Secrete LH

Q28. Which of the following is an example of positive feedback?

a) LH surge leading to ovulationb) Progesterone inhibiting LHc) Estrogen inhibiting FSHd) Inhibin inhibiting FSH

Q29. The duration between ovulation and menstruation is approximately

a) 7 daysb) 14 daysc) 21 daysd) 28 days

Q30. The structure formed from empty Graafian follicle after ovulation

a) Corpus albicansb) Corpus luteumc) Primary follicled) Secondary follicle

Q31. Assertion: Human sperm has acrosome. Reason: Acrosome contains enzymes for zona pellucida penetration.

a) Both true, Reason correct explanationb) Both true, Reason not correct explanationc) Assertion true, Reason falsed) Both false

Q32. The hormone that stimulates Leydig cells

a) FSHb) LHc) GnRHd) Inhibin

Q33. The process by which blastocyst becomes embedded in endometrium

a) Cleavageb) Implantationc) Gastrulationd) Organogenesis

Q34. Which of the following is not a part of female external genitalia?

a) Mons pubisb) Labia majorac) Ovariesd) Clitoris

Q35. The primary function of prostate gland secretion is

a) Provide nutrition to spermb) Alkaline pH to neutralize vaginal acidityc) Motility to spermd) Both b and c

Q36. Assertion: Pregnancy can be detected by presence of hCG in urine. Reason: hCG is secreted by trophoblast.

a) Both true, Reason correct explanationb) Both true, Reason not correct explanationc) Assertion true, Reason falsed) Both false

Q37. The number of chromosomes in spermatid is

a) 23b) 46c) 22d) 44

Q38. Which hormone peaks just before ovulation?

a) FSHb) Estrogenc) LHd) Progesterone

Q39. The inner cell mass of blastocyst differentiates into

a) Ectoderm, Mesoderm, Endodermb) Trophoblastc) Placentad) Amnion

Q40. Assertion: Parturition is a neuroendocrine mechanism. Reason: Fetal ejection reflex triggers oxytocin release.

a) Both true, Reason correct explanationb) Both true, Reason not correct explanationc) Assertion true, Reason falsed) Both false

Q41. The cells that produce androgen binding protein

a) Leydig cellsb) Sertoli cellsc) Spermatogoniad) Primary spermatocytes

Q42. The hormone that causes proliferation of endometrium

a) Progesteroneb) Estrogenc) LHd) FSH

Q43. The umbilical arteries carry

a) Oxygenated bloodb) Deoxygenated bloodc) Nutrient rich bloodd) Lymph

Q44. Assertion: Spermiogenesis and spermiation are different. Reason: Spermiogenesis is transformation of spermatid, spermiation is release of sperm.

a) Both true, Reason correct explanationb) Both true, Reason not correct explanationc) Assertion true, Reason falsed) Both false

Q45. The failure of corpus luteum to function leads to

a) Amenorrheab) Menorrhagiac) Infertilityd) Early abortion

Q46. The hormone that stimulates milk synthesis

a) Oxytocinb) Prolactinc) Estrogend) Progesterone

Q47. Which of the following is not true about oogenesis?

a) Begins before birthb) Completes only after fertilizationc) Produces 4 functional ovad) Occurs in ovary

Q48. The structure that connects embryo to placenta

a) Chorionb) Umbilical cordc) Amniond) Allantois

Q49. Assertion: LH surge is responsible for ovulation. Reason: High estrogen level triggers LH surge.

a) Both true, Reason correct explanationb) Both true, Reason not correct explanationc) Assertion true, Reason falsed) Both false

Q50. The primary spermatocyte undergoes

a) One mitotic divisionb) One meiotic divisionc) Two meiotic divisionsd) No division

🔑 ANSWER KEY - HARD LEVEL

1-a, 2-a, 3-c, 4-b, 5-b, 6-b, 7-b, 8-a, 9-b, 10-c, 11-a, 12-a, 13-a, 14-a, 15-a, 16-c, 17-d, 18-a, 19-b, 20-d, 21-b, 22-a, 23-c, 24-a, 25-b, 26-a, 27-b, 28-a, 29-b, 30-b, 31-a, 32-b, 33-b, 34-c, 35-d, 36-a, 37-a, 38-c, 39-a, 40-a, 41-b, 42-b, 43-b, 44-a, 45-d, 46-b, 47-c, 48-b, 49-a, 50-b